| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
콜로이드계면화학_포스터 |
| 제목 |
Biomimetic self-assembly of an novel amphiphilic polyaspartamide nanocell |
| 초록 |
Nanosized self-aggregates with various morphologies are being increasingly studied for targeted delivery of diagnostic and therapeutic molecules. Therefore, this study presents synthesis of an amphiphilic polyaspartamide copolymer grafted with porphyrin molecules that can form micelle-like self-aggregates in an aqueous solution. Increasing the degree of substitution of porphyrin molecules drives the polymer to self-assemble into a rod like structure be caused by noncovalent interactions between aromatic rings of porphyrin. Further introduction of the metal ions into the packing structure leads to a significant increase in the uptake of oxygen molecules. The results will serve to improve the efficiency of targeted delivery for a molecular ultrasound imaging with various biomedical modalities. |
| 저자 |
정재현, 한사라, 조성우, 김희진, 조윤나
|
| 소속 |
숭실대 |
| 키워드 |
Nanocell; polyaspartamide; self-assembly; prophyrin
|
| E-Mail |
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