| 초록 |
Surface properties of poly( ε-caprolactone)diol-based polyurethane(PU)/poly(ethylene glycol) diacrylate(PEGDA) IPNs that have been investigated for implatable biomaterial at the hydrated state are very importanat, considering the physiological environment in a body where they will be used. Especially, the change of surface morphology and the surface energy was essential for the biomedical research, because it is a key factor on the adsorption of proteins and blood coagulating factors. In our study, the surface morphology of PU/PEGDA IPNs swollen in water was observed in water using the unit for observing in water of AFM. The effect of surface morphology on blood-compatibility was investigated by in-vitro platelets adhesion test. And the effect of surface morphology on protein adsorption was also investigated using UV spectrometer. From the observing the morphology at hydrated state, we can see that PU/PEGDA IPNs at hydrated state have stable micro-separated morphology in water. |
