| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 | 20권 1호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Stabilization of Epidermal Growth Factor by Visible Light-Curing Furfuryl Alginate Compound for Wound Healing |
| 초록 | A visible light-curable polysaccharide was prepared and was contained with epidermal growth factor (EGF) for wound healing application. Alginate was modified with furfurylamine (F-alginate). The structure of F-alginate was identified by 1H-NMR and UV/vis spectroscopy. Photo-crosslinking was evaluated by micropatterning and weight measurement. Swelling ratio was also determined. To verify its applicability in wound healing, cytotoxicity test was carried out. After the confirmation of no cytotoxicity of F-alginate and murine EGF release from the system, cell proliferation, antibacterial activity, and animal test were performed on the system. In conclusion, it was demonstrated that F-Alginate was useful for wound healing. Acknowledgements This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and future Planning (No. NRF-2014R1A2A1A11052623) |
| 저자 | 노승현, 김은혜, 정진홍, 한가득, 김재원, 손태일 |
| 소속 | 중앙대 |
| 키워드 | bioengineering; biomedical applications; biomaterials; photochemistry; polysaccharides |
