| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 봄 (04/12 ~ 04/13, 제주 ICC) |
| 권호 |
32권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Self-crosslinking injectable hydrogels based on poly(aspartate) and poly(ethylene glycol) |
| 초록 |
Injectable polymer hydrogels have been widely explored for a number of biomedical applications, including drug delivery and tissue engineering. In particular, hydrogels derived from poly(amino acid)s have shown many advantages by expressing degradability and excellent biocompatibility. In this work, we describe a new self-crosslinking injectable hydrogel based on acrylated poly(aspartate) and poly(ethylene glycol) disulfhydryl. No organic solvent, elevated temperature, or harsh pH is required in the formulation of hydrogels or patient administration processes, thereby making it attractive for delivery of fragile therapeutics, such as proteins. Acknowledgement. This study was supported by a grant (code #:10024816) from R&D Program for “International Joint Technology Development Project” by Korea Ministry of Commerce, Industry and Energy. |
| 저자 |
이홍재, 김찬우, 최형우, 김경자, 김소연, 김성은, 이상천
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| 소속 |
요업기술원 나노소재응용본부 나노바이오융합팀 |
| 키워드 |
injectable hydrogel; self-crosslinking; poly(aspartate); poly(ethylene glycol); protein delivery
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| E-Mail |
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