| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 | 27권 2호, p.315 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Wettability Improvement and Sterilization of Polymeric Scaffold by Plasma Treatment |
| 초록 | Polymeric scaffolds for tissue engineering must be either manufactured aspectically or sterilized after processing. For sterilization processing, the general requirement of polymeric scaffolds are non-toxicity, tissue compatibility, and preservation of its properities. The goal of study was to determine the optimal sterilization technique without causing damage slightly to successful tissue engineering. The plasma sterilizaion method was compared to three well-established technique ; 70 % ethanol, ethylene oxide, and γ-irradiation. We evaluated molecular weight and change of pore structure by various sterilization methods. the former was evaluated by gel permeation chromatography (GPC) and the laster by scanning electron microscopy (SEM), respectively. We observed increasing wettability of plasma treated scaffold according to 0.01 w/v % brilliant blue dye dropping method and water absorption. Our results show that plasma treatment is the most suitable method for sterilizing polymeric scaffolds for tissue engineering applications. Acknowledgment: This work was supported by MOWH(IMT-2000, 01-PJ11-PG9-01NT00-0011). |
| 저자 | 김인영1, 장지욱2, 신필경3, 강조아*, 강길선*, 이봉, 이해방** |
| 소속 | 1부경대, 2*전북대, 3**한국화학(연) |
| 키워드 | P |
