| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 봄 (04/15 ~ 04/17, 호텔인터불고(대구)) |
| 권호 |
13권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Temperature sensitive drug delivery system usingPNIPAAM and Chitosan |
| 초록 |
New thermosensitive nanoparticles, based on PNIPAAm-AA core and chitosan shell structure, were designed and synthesized for the controlled release of the loaded drug. The particle size of synthesized nanoparticles was varied from 380 nm to 25 nm as temperature of the dispersed medium increased. LMWSC-conjugated nanoparticles of 2wt% MBA, crosslinking monomer, leaded to a stable aqueous dispersion at concentration of 1mg/1ml otherwise showed gel collapse temperature. The effect of temperature on the dynamic behavior of the PNIPAAm chains were also studied by dynamic light scattering and UV-Vis absorption measurements. |
| 저자 |
정현, 김양배, 허선행, 남정표, 김동곤, 정영일, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
LMWSC; PNIPAAm; Lower critical solution temperature; Thermosensitive
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| E-Mail |
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