화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크)
권호 13권 2호
발표분야 고분자(포스터)
제목 Preparation of Cisplatin-Incorporated Carboxymethyl Water-soluble Chitosan Micelles
초록 In this study, we prepared nanoparticles based on the formation of an ion complex between carboxymethyl water-soluble chitosan (CMCh) and cisplatin. Cisplatin (cis-dichlorodiammineplatinum(II): CDDP) is one of the most widely used antitumor drugs in the treatment of a variety of solid tumors. CDDP loaded CMCh(Cis-CMCh) micelles were prepared by ion-complex and investigated by 1H-NMR, FT-IR (Fourier transform infrared), TEM (scanning electron microscopy),DLS (dynamic light scattering), release behavior and cells cytotoxicity measurement.
저자 남정표, 정현, 김원석, 최창용, 정영일, 장미경, 나재운
소속 순천대
키워드 carboxymethyl chitosan; LMWSC; Cis-CMCh; cisplatin
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