학회 |
한국공업화학회 |
학술대회 |
2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크) |
권호 |
13권 2호 |
발표분야 |
고분자(포스터) |
제목 |
Preparation of Cisplatin-Incorporated Carboxymethyl Water-soluble Chitosan Micelles |
초록 |
In this study, we prepared nanoparticles based on the formation of an ion complex between carboxymethyl water-soluble chitosan (CMCh) and cisplatin. Cisplatin (cis-dichlorodiammineplatinum(II): CDDP) is one of the most widely used antitumor drugs in the treatment of a variety of solid tumors. CDDP loaded CMCh(Cis-CMCh) micelles were prepared by ion-complex and investigated by 1H-NMR, FT-IR (Fourier transform infrared), TEM (scanning electron microscopy),DLS (dynamic light scattering), release behavior and cells cytotoxicity measurement. |
저자 |
남정표, 정현, 김원석, 최창용, 정영일, 장미경, 나재운
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소속 |
순천대 |
키워드 |
carboxymethyl chitosan; LMWSC; Cis-CMCh; cisplatin
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E-Mail |
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