| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크) |
| 권호 |
13권 2호 |
| 발표분야 |
석유화학윤활유(포스터) |
| 제목 |
Graphene-based Biosensor for Specific DNA Sequence Detection |
| 초록 |
In this study, we explored a potential of graphene oxide (GO) sheets as a fluorescence probe for biological applications. The properties of water-solubility due to the hydrophilic functional groups on the GO surface and the unique fluorescence emission signal at 546 nm allow the microsized GO sheets to be used for detecting specific DNA-DNA hybridization event. A DNA probe is immobilized on the GO surface covalently by an amide bond, and when the probe captures a gold nanoparticle (Au NP) labeled target DNA, the fluorescence intensity of GO is drastically reduced due to the FRET/electron transfer phenomenon between GO and Au NP. |
| 저자 |
Liu Fei1, 최종영2, 서태석3
|
| 소속 |
1Department of Chemical and Biomolecular Engineering, 2KAIST, 3Daejeon |
| 키워드 |
Graphene oxide; Gold nanoparticles; DNA detection
|
| E-Mail |
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