| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 봄 (04/12 ~ 04/13, 서울대학교) |
| 권호 | 27권 1호, p.271 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Induction and Growth of Neurites of DRG Neurons on the Wettability Gradient PE Surfaces |
| 초록 | Dorsal root ganglia (DRG) neurons have both central and peripheral myelinated processes in situ, they have been a uniquely valuable and biologically relevant system for the study of myelination in tissue culture. There are many factors for more neurites of the DRG neurons by neurotrophic factors i.e. nerve growth factors (NGF), leukemia inhibitory factors (LIF), and neuronal nitric oxide synthase (nNOS). The effect of surface wettability on the different types of cells was an important role for cell adhesion and proliferation. The purpose of this study is neurites formation on polymer surfaces with different wettability. Induction and growth of neurites from the adult rat DRG neurons attached on the PE surfaces with different hydrophilicity were investigated using the wettability gradient PE surfaces prepared by corona discharge treatment. In conclusion, surfaces wettability plays an important role for neurites formation on the polymer surfaces for axon regeneration. Acknowledgment: This work was supported by MOCIE. |
| 저자 | 신필경1, 이상진*2, 이 봉3, 강길선**, 이해방* |
| 소속 | 1부경대, 2*한국화학(연), 3**전북대 |
| 키워드 | |
