| 학회 |
한국고분자학회 |
| 학술대회 |
2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
41권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Colorimetric nanosensor with Gold nanorod(GNR) conjugated antibody for detecting Influenza virus |
| 초록 |
Recently, various nanobiosensors have been developed to detect wide range of pathogens causing pandemic emergence. Although they have got improved in some degree, they still have significant difficulties that had to be overcome in terms of time-requirement, insufficiency of sensitivity and selectivity. There is the need of reducing time for identifying pathogens on account of high contagiousness. Furthermore, selectivity and sensitivity should be also agonized over for accurate detection. As an alternative methodology, we designed a fast colorimetric method for detecting Influenza virus by targeting Hemagglutinin (HA). Using sulfide linkage, antibody binding to HA was tethered on gold-nanorod(GNR) which was template and also indicator because of visible alteration during the following process. It revealed that the designed method based on immunoassay is feasible application as an enhanced nanobiosensor for detecting Influenza virus without additional equipment. |
| 저자 |
박근선1, 김현욱1, 나운성2, 염민주2, 임종우1, 윤다연1, 김지혜1, 천해진1, 기지선1, 송대섭2, 함승주1
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| 소속 |
1연세대, 2고려대 |
| 키워드 |
goldnanorod; antibody; nanobiosensor
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| E-Mail |
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