| 학회 |
한국재료학회 |
| 학술대회 |
2018년 가을 (11/07 ~ 11/09, 여수 디오션리조트) |
| 권호 |
24권 2호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Nanobiosensor comprising conductive polymer enclosed in amphiphilic polymer vesicles for Selective detection of Influenza A virus |
| 초록 |
Nanobiosensor has been selected as a method for detecting wide range of pathogens to prevent pandemic emergence. As one of promising platform, conductive polymer based nanobiosensor has a distinct advantage in the way that its ability to sensitive and rapid detection. In this study, we designed a detection system which is conductive poly aniline based on polymersome conjugated with peptide for specific recognition of influenza A virus. We synthesized poly aniline polymerized within a polymersome consisting of methoxy polyethylene glycol-block- polyphenylalanin co-polymer (mPEG-b-pPhe). Then we conjugated the polymersome with peptide binding to hemagglutinin located on the surface of influenza virus. In the presence of Influenza virus, the nanoparitlce aggregated with the virus, exposing absorption wave length change. These results indicate that this nanobiosensor could be a potential candidate in terms of detecting influenza virus. |
| 저자 |
박근선1, 김현욱2, 임종우1, 박채원1, 함승주1
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| 소속 |
1연세대, 2고려대 |
| 키워드 |
<P>conductive polymer; biosensor; influenza virus</P>
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| E-Mail |
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