| 초록 |
Different enantiomers result in different effects in various industries, which has required optically pure enantiomers and stimulated the development of new and effective chiral separation methods. In this research, a new technique for the separation of chiral molecules using homochiral lipid membranes is introduced, which is expected to achieve both high permeability and selectivity at the same time. The ultrathin freestanding separation membrane was created by a spontaneous self-assembly of lipid molecules. Then, membrane transport of each enantiomer was measured respectively. Once the chiral-selective transport is confirmed, a racemic compound was provided and the enantiomeric excess after membrane transport was identified via circular dichroism (CD) spectroscopy. Further modification of our lipid bilayer composition is expected to increase the separation efficiency and give information of key factors for this unconventional chiral separation method. |
