초록 |
Polymerized poly(ethylene glycol) diacrylate(PEGDA) was used as container of Fe3O4 nanoparticles and fluorescent silica particles. A droplet-based microfluidic method for the preparation of monodisperse PEGDA microdroplets was developed. Prepared PEGDA microdroplets have uniform size and fine round shape, with asizearound 60 μmusing 50 μm orifice flow-focusing device. The size of microdroplets can be controlled through the changing orifice width and continuous phase flow rate. Successful fabrication of PEGDA microdroplets entrapping Fe3O4 nanoparticles and fluorescent silica particles were confirmed by attraction to external magnetic field and exhibition of the fluorescence, respectively. Due to the biocompatibility of PEGDA and the magnetism of Fe3O4, this microparticle could be applied to pharmaceutical field such as a smart drug delivery. |