| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터) |
| 권호 |
43권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Gram scale synthesis and aplication of biocompatible carbon nano Onions: A versatile fluorescence nanomaterial for multi-channel glutathione sensing |
| 초록 |
Biocompatible White-light-emitting nanomaterials with multichannel fluorescence (MCF) emissions are gaining significant importance for diverse biomedical applications. Here, we present a biological precursor mediated novel method for the gram scale synthesis of White-light emitting carbon nano-onions (WCNOs). The physicochemical characterizations confirm that the developed WCNOs were negatively charged (-50 mV) and sized ~15 nm, with abundant carboxyl and hydroxyl groups on their surface. The PL studies determine the MCF blue, green and red fluorescence from the WCNO nanomaterials. The In vitro and In vivo characterizations further confirmed the MCF from the CNOs. WCNOs were further coated with Manganese oxide, to develop stimuli responsive glutathione biosensor. Such nanocomposite was able to detect and image the GSH responsive MCF imaging in both cells and animals. In conclusion, the developed WCNOs could be promising nanomaterial for diverse biomedical applications |
| 저자 |
Vishnu Revuri, 안정만, 이용규
|
| 소속 |
Korea National Univ. of Transportation |
| 키워드 |
White light emission; Multichannel fluorescence; Glutathione; Biosensor; Manganese oxide.
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| E-Mail |
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