| 학회 |
한국화학공학회 |
| 학술대회 |
2011년 봄 (04/27 ~ 04/29, 창원컨벤션센터) |
| 권호 |
17권 1호, p.364 |
| 발표분야 |
생물화공 |
| 제목 |
Preparation of molecularly imprinted submicron/nanoscale beads for chiral resolution of phenylalanine racemate solution |
| 초록 |
Molecularly imprinted polymers (MIPs) have been produced for applications in vitro diagnostics, therapeutics and separations. Recent developments in the area of MIP nanoparticles might offer solutions to several problems associated with performance and application. MIP submicron/nanoscale beads selective for L-Phenylalanine (L-Phe) and D-Phe as well as non-imprinted beads were prepared by modified suspension polymerization involving agitation of the reaction mixture at high rotation speed under safe radical conditions. The adsorption capacity and selectivity of L-Phe imprinted submicron/nanoscale beads were higher than the adsorption capacity and selectivity of D-Phe imprinted and non-imprinted submicron/nanoscale beads. FE-SEM analyses showed that the presence of template had caused greater effect on the beads sizes. L- and D-Phe imprinted beads were larger in size (100nm~1.5m) than non-imprinted nanobeads (100nm~800nm). FT-IR study revealed the structural characteristics of the prepared Phe imprinted and non-imprinted beads. |
| 저자 |
Nasrullah Shah, Mazhar-ul-Islam, 하정환, 박중곤
|
| 소속 |
경북대 |
| 키워드 |
Molecularly imprinted submicron/nanoscale beads; Modified suspension polymerization; Safe radical conditions
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
