| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO)) |
| 권호 | 22권 1호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Analyze the Biocompatibility of PLCL Porous Scaffold Using Salt Leaching Method |
| 초록 | Biodegradable polymers are widely used in medical applications. In particular, PLCL is a synthetic copolymer of PLA and PCL and displays slower degradation and high elasticity. PLCL can be used in tissues alternating compression and relaxation, such as hear, blood vessel, and skin tissues. In this study, we investigated the feasibility whether PLCL can be used as a bone substitute. 3D porous PLCL scaffold was fabricated via salt leaching method using a solid porogen. The surface morphology, 3D architacture and interconnectivity of pores evaluated. In addition, we examined the biocompatibility of the scaffold using osteoblastic cell-line. Our results displayed that the PLCL did not cause cytotoxic effect and stimulated the cell activity. This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717). |
| 저자 | 김정헌, 박진우, 이수희, 오지영, 이우걸 |
| 소속 | 단국대 |
| 키워드 | Scaffold; PLCL; Biocompatibility |
