| 학회 |
한국화학공학회 |
| 학술대회 |
2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
| 권호 |
20권 2호, p.1525 |
| 발표분야 |
생물화공 |
| 제목 |
Biosynthesis of poly (3-hydroxybutyrate-co-3-hydroxyvalerate) using recombinant Escherichia coli |
| 초록 |
Due to its biodegradability and biocompatibility, polyhydroxyalkanoate has drawn many interest as a termoplastic. Among the different types of PHA co-polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] has lower melting point and better flexibility compared to the 3-hydroxybutyrate. Until now, toxic second auxiliary carbon source is being added for the production of P(3HB-co-3HV). Therefore, metabolically engineered Escherichia coli that can synthesize 3HB-CoA and 3HV-CoA in a stable manner with the ratio being controlled was developed from glucose independent of the feeding of the carbon source.“This work was supported by the Technology Development Program to Solve Climate Changes from National Research Foundation of Korea (Development of systems metabolic engineering platform technologies for biorefineries;NRF-2012-C1AAA001-2012M1A2A2026556) and Intelligent Synthetic Biology Center (2011-0031963) of Korea through the Global Frontier Research Program of the Ministry of Education, Science and Technology (MEST).” |
| 저자 |
양정은1, 최용준2, 박시재3, 이승환4, 이상엽1
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| 소속 |
1한국과학기술원, 2한국원자력(연), 3명지대, 4한국화학(연) |
| 키워드 |
Polyhydroxyalkanoate; Metabolic engineering; Bio-based polymer
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| E-Mail |
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| VOD |
VOD 보기 |
| 원문파일 |
초록 보기 |
