| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Drug-releasing control using UV-curable alginate derivative for wound-healing on urethane form |
| 초록 |
Alginate is a natural polymer having biodegradable and biocompatibility. Azidophenyl Alginate(Az-Alginate) was prepared for medical applications. FT-IR analysis and 1H-NMR were conducted for the structure of the Az-Alginate. Modified urethane form immobilized Protein drug was made by photo-crosslinking of a photo-reactive functional group (Azido group) introduced into the Alginate. Modified urethane form can be expected that it is able to photo-immobilize protein drug and apply to drug-releasing control for wound healing. To evaluate the potential applications as a drug delivery agent, should be photo-immobilized fluorescent proteins(FITC-BSA) and confirmed by a fluorescent microscope. And cytotoxicity test, photo curing test and protein releasing test were practiced. Modified urethane form was made slowly release the drug. So Az-Alginate on urethane form is considered to be able to develop as drug-releasing control agent for wound healing. |
| 저자 |
김재원, 김은혜, 한가득, 노승현, 손태일
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| 소속 |
중앙대 |
| 키워드 |
Az-Alginate; urethane form; drug-releasing control agent; wound healing
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| E-Mail |
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