| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
콜로이드·계면화학_포스터 |
| 제목 |
Morphology Control of Cisplatin-incorporated Polymeric Nanoparticles with Cholesterol-functionalized Liner/Brush Block-copolymers |
| 초록 |
We present an altered morphology of cisplatin-incorporated nanoparticles with cholesterol-end-modified linear/brush-type double-hydrophilic block-copolymers (DHBCs). Compared against the cholesterol-free counterpart, which generated a typical core/shell-structure with cisplatin-incorporated spherical core, employing the cholesterol end groups on the DHBCs leads to the formation of toroidal core inside the nanoparticle. Additionally, the cholesterol-modification further enhanced the metal-mediated self-assembly efficiency of DHBCs by the increased hydrophobicity of cholesterol terminal ends. |
| 저자 |
김여진, 이상민
|
| 소속 |
가톨릭대 |
| 키워드 |
Block-copolymer; Salf-assembly; Polymeric Nanoparticles; Morphology Control
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| E-Mail |
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