| 학회 | 한국화학공학회 |
| 학술대회 | 2002년 봄 (04/26 ~ 04/27, 강원대학교) |
| 권호 | 8권 1호, p.1245 |
| 발표분야 | 생물화공 |
| 제목 | 단백질 3차 구조를 구성하는 아미노산의 구조적 성질들의 분자 수준 해석과 통계적 해 석 |
| 초록 | Molecular calculations, and statistical analyses, were performed to investigate the relationships between residual conformational properties of amino acid as building blocks in three-dimensional protein structures. 100 monomeric protein structures were employed as representative model systems. In each protein, various residual conformational properties, such as; exposure ratio, packing value, surface area, solvation free energy, residual energy, flexibility, secondary structure, and several stabilizing interactions, were calculated. After each residual property of all the model proteins were statistically analyzed, distinct and similar patterns were obtained according to the amino acid type. For arranging several residual conformational properties, the dendrogram describing the conformational relationship among 20 amino acids in a protein structure was proposed via hierarchical cluster analysis. The results of the residual conformational property patterns, and clusters among the amino acids, could serve as basic data for analyzing local protein structure, and for predicting local protein function. |
| 저자 | 백승필, 최유성, 민경선, 유영제 |
| 소속 | 서울대 |
| 키워드 | Residual conformational property; Statistical analysis; Protein structure |
| , , , | |
| 원문파일 | 초록 보기 |
