화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 37권 2호
발표분야 기능성 고분자
제목 DNA Sensing Application of Conjugated Polymer Nanospheres via FRET
초록 Deoxyribonucleic acid(DNA) is a nucleic acid containing the genetic instructions used in the development and functioning of all known living organisms. The conjugated polymer nanospheres have a good potential to be functional materials that can be used in many applications such as material science and biological systems. In this study, we prepared conjugated polymer nanospheres by precipitation method. Then, we confirmed the size of nanospheres by DLS and SEM, and analyzed optical properties using PL and UV spectroscopy. We studied an application of complementary DNA with ssDNA on conjugated polymer nanospheres. The ssDNA on conjugated polymer nanospheres was incubated with complementary TAMRA-DNA. The absorption of the complementary TAMRA- DNA has a good overlap with the emission of the polymer nanospheres. As a result, we confirmed fluorescence change via fluorescence resonance energy transfer (FRET).
저자 노재국, 장근석, 김대근, 이택승
소속 충남대
키워드 conjugated polymer nanoshperes; DNA; FRET
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