| 학회 |
한국재료학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/02, 성균관대학교) |
| 권호 |
13권 2호 |
| 발표분야 |
나노생체재료 |
| 제목 |
IN VITRO MODEL OF BIOACTIVE BI-STRUCTURED CERAMIC-POLYMER NANOHYBRIDS |
| 초록 |
Synthetic model of a large crack-free monolithic ceramic-polymer hybrid, which was synthesized using triethoxysilane end-capped poly (tetramethylene oxide) (Si-PTMO) modifed tetra-ethoxysilane (TEOS)-PTMO bulk, was examin-ed in the CaO-SiO2-PTMO sol-gel system. Bulk precursor with nominal mass ratio of PTMO: TEOS = 80: 20 and surface precursor with nominal molar ratio of TEOS: Ca(NO3)2 = 1: 0.3 were subjected to hybrid-ization through hydrolysis and condensation process, producing a bi-structured hybrid, in which poly-meric bulk was molecular hybridized with bioactive silicate surface. Spectroscopic and microscopic cha-racterizations revealed that the surface of hybrid was typical bioactive silicate. In vitro study using a simulated body fluid (SBF) revealed that the hybrid formed an osteo-inductive apatite on its surface within only 6 hours, suggesting bioactive materials with high capability of tissue integration as well as polymeric physical properties. |
| 저자 |
K.-Y. Lee1, H.-J. Choi2
|
| 소속 |
1School of Advanced Materials Engineering, 2Yonsei Univ. |
| 키워드 |
bioactive; bi-structured; hybrid
|
| E-Mail |
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