초록 |
Electrospraying technology has been developed for more than four decades, which provided unique capabilities for mass spectroscopy and coating applications. Particles prepared by electrospraying have been investigated for drug delivery applications, since its size and morphology can be tuned by the electrohydrodynamic force. Furthermore, the core-shell morphology with controllable shell thickness and the anisometric particle morphology of polymers were successfully achieved. In this study, we designed the co-axial electrospraying systems for protein drug delivery and other applications. The size of core/shell particles was easily controlled by the flow rate of outer solutions. The use of various inner solutions of water-soluble polymers resulted in various core/shell structures. Unique release properties and assembly behaviors were achieved in the systems of various core/shell structures. |