| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Fabrication of Yolk-Shell Type Gold Nanorattles for Chemotherapy, Targeting, and Hyperthermia |
| 초록 |
This study presents Multifunctional Yolk/Shell Type Gold Nanorattles focused on targeting, chemo-Therapy, Hyperthermia to kill the tumor cells. Gold nanorattles have proven to be promising capsules in the area of drug delivery system. Active targeting, chemo-therapy, and hyperthermia have get the limelight to eliminate tumor cells effectively and minimize adverse effect. In this work, Folic acid(FA), the tumor specific targeting ligand, and gold nanorods (GNRs) which strongly absorb near-infrared (NIR) radiation and produce localized cytotoxic heat upon NIR irradiation are used in this nanorattles as the carrier of doxorubicin. It is expected that this particles can be used as hyperthermia to efficiently kill tumorigenic cells in the area of drug-delivery system. |
| 저자 |
민지홍, 정의석, 김민수, 조강희, 윤병주, 고원건
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| 소속 |
연세대 |
| 키워드 |
chemotherapy; hyperthermia; cancer
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| E-Mail |
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