| 초록 |
Recently, there have been many studies on the fabrication of 3D printed scaffolds using gelatin, a natural polymer. However, it is still a challenge to use pure gelatin hydrogels with poor physical properties to obtain a uniform 3D printed structure. In this study, we optimized the fabrication of pure gelatin 3D scaffolds using modified 3D printing and adjustment of various process parameters. We investigated the effect of concentration and viscosity (rheological properties) on melting temperature for the fabrication of optimized gelatin 3D printed scaffolds. The uniformity of 3D printed scaffolds was confirmed using scanning electron microscopy. Confocal microscopy images showed that human dermal fibroblasts exhibited high cell proliferation rate for 7 days of culture in optimized 3D scaffolds. This study will be useful to fabricating uniform 3D scaffolds by adjusting 3D printing process parameters. |
