학회 | 한국공업화학회 |
학술대회 | 2007년 봄 (05/11 ~ 05/12, 계명대학교) |
권호 | 11권 1호 |
발표분야 | 정밀화학 |
제목 | Enantioselective synthesis of atenolol catalyzed by Heterobimetallic Co (III) salen complexes |
초록 | Synthesis of (S)-atenolol was achieved from kinetic resolution of epichlorohydrin with Butyl p-hydroxy acetate and hydrolytic kinetic resolution (HKR) of 1-[p- [(butoxycarbonyl) methyl] phenoxy]-2,3-epoxypropane catalyzed by heterobimetallic Co (III) salen complexes displayed excellent enantioselectivty and good yield (98% ee, 35% yield). Heterobimetallic Co (III) salen complexes are characterized by ESCA, EXFAS and ESI-MS analysis. |
저자 | 라울, 김건중 |
소속 | 인하대 |
키워드 | : Kinetic resolution; homogeneous catalysis; Heterobimetallic complexes; atenolol. |