화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2007년 봄 (05/11 ~ 05/12, 계명대학교)
권호 11권 1호
발표분야 정밀화학
제목 Enantioselective synthesis of atenolol catalyzed by Heterobimetallic Co (III) salen complexes
초록 Synthesis of (S)-atenolol was achieved from kinetic resolution of epichlorohydrin with Butyl p-hydroxy acetate and hydrolytic kinetic resolution (HKR) of 1-[p- [(butoxycarbonyl) methyl] phenoxy]-2,3-epoxypropane catalyzed by heterobimetallic Co (III) salen complexes displayed excellent enantioselectivty and good yield (98% ee, 35% yield). Heterobimetallic Co (III) salen complexes are characterized by ESCA, EXFAS and ESI-MS analysis.
저자 라울, 김건중
소속 인하대
키워드 : Kinetic resolution; homogeneous catalysis; Heterobimetallic complexes; atenolol.
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