| 초록 |
The novel zwitter ionic surface modified MCM41 mesoporous silica (MSN) was prepared by post condensation method. Phospholipid moieties were generated by multistep surface modification. Immobilization and phosphorylcholine (PC) modification were characterized by Fourier transform infrared spectroscopy, XRD, SEM, thermo gravimetric analysis and N2 adsorption-desorption analysis. The studies revealed the successful introduction of phosphorylcholine (PC) groups at the surface, the modified MSNs were found maintained the original meso-structure of MCM41 whereas, the pore diameter and surface area were reduced by modification. The adsorption studies of bovine serum albumin showed a significant reduction by the introduction of PC groups onto MCM41 |
