| 초록 |
There have been made consistent efforts to develop bone substitutes not only composed of bioactive and biodegradable material but also having a high mechanical property including strength and flexibility. Polylactic acid (PLA), a biodegradable synthetic polymer, is too brittle to use as a bone substitute. Here incorporation of cellulose nanofibril (CNF), that is biodegradable and having excellent physical property comparable with carbon fiber, in PLA matrix has been tried by melt-mixing. In order to enhance dispersion, CNF was surface-modified by inorganic materials, which also improves thermal stability of CNF. Flexural strength of the composite was tested and the composite was applied to fractured femur of rabbit to observe effect of bone fixation. |
