| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
정밀화학 |
| 제목 |
Mode of antibiotic action and their antibacterial activity on the bacterial membrane of the peptides with an influence of alternating pattern of K and W residues |
| 초록 |
The antibacterial peptides need to develop that are non resistant to the rapid emergency of bacterial infections. Further increasing cationic and hydrophobicity in the scrambled peptide was demonstrated to correlate with peptide beta sheet and self associating ability in aqueous environment. Thepeptides kill the bacteria by membrane disruption was evaluated through membrane potential depolarization assay, membrane permeability. Interaction of these peptides with model liposomes vesicles was examined using tryptophan fluorescence.This study was supported by IPET(Korea Institute of planning & Evaluation for Technology in Food, Agriculture, Forestry & Fisheries) Research Fund in 2009. |
| 저자 |
나재운1, 박윤경2
|
| 소속 |
1순천대, 2조선대 |
| 키워드 |
antibiotic; antibacterial activity; antibacterial peptides
|
| E-Mail |
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