| 초록 |
Recently, water-soluble, conjugated polymers have attracted much attention because of their detection applications, such as DNA, proteins, and biological agents. Conjugated polymers, especially, were used for sensory materials due to large signal amplification by trace amount of analytes. Conventional conjugated polymers, however, are only soluble in organic solvents, because they have commonly a hydrophobic and rigid main chain. This resulted in a poor solubility in water and subsequent fluorescent quenching by micelle formation in an aqueous phase. Herein, we synthesized water-soluble poly(para-phenylene) copolymer containing water-solubilizing groups. Furthermore for bio-applications, water-soluble poly(para-phenylene) copolymer include maleimide as a receptor in a main chain connected covalently. Widely utilized in bioconjugation, maleimides are often used to detect biomolecules with thiol group by a facile Michael addition. |
