| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스)) |
| 권호 |
10권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
Characterization of LMWSC-DNA complex for Gene Carrier |
| 초록 |
In this study, unlike synthetic polymers with toxicity, we used low molecular water soluble chitosan(LMWSC) having a free amine group for gene delivery. The LMWSC efficiently condensed plasmid DNA into nanosized ion-complexes. An investigation of gene condensation and the stability of complexes were performed by a gel retardation assay. The size and zeta potentials of complexes were measured by dynamic light scattering(DLS) Cytotoxicity of complexes was performed by MTT assay using 293T cell and HeLa cell. |
| 저자 |
장민자1, 나재운1, 김동곤1, 권중근2, 장미경1
|
| 소속 |
1순천대, 2조선이공대 |
| 키워드 |
gene carrier; LMWSC
|
| E-Mail |
|
