| 학회 |
한국고분자학회 |
| 학술대회 |
2006년 봄 (04/06 ~ 04/07, 일산킨텍스) |
| 권호 |
31권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
pH-Senstive, Hydroxypropylmethacrylate (HPMA)-based Hydrogels: Controlling of swelling/deswelling and drug release behaviors by N,N'-dimethylethylaminomethacrylate (DMA) |
| 초록 |
pH-Sensitive hydrogels are of particular interest in controlled drug delivery. Hydroxypropylmethacrylate (HPMA)-based hydrgels are one of the most widely used. The goal in this study is to manipulate the swelling/deswelling and drug release behaviors of HPMA-based hydrogels by controlling the physical and chemical properties of the copolymer network. Different hydrogels were prepared by free radical copolymerization of HPMA and DMA (N,N'-dimethylethylaminomethacrylate). Swelling characteristics and drug release profiles were investigated as a function of pH values. |
| 저자 |
최순모1, 한태희2, 김수현3, 조용우3, 류원석1, 한성수1
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| 소속 |
1영남대, 2한양대, 3아산생명과학(연) |
| 키워드 |
Hydrogel; pH-Sensitive; Drug Delivery; HPMA
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| E-Mail |
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