| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Bacterial Adherence on Brush Polymers Bearing Zwitterionic Sulfobetaine Moieties |
| 초록 |
A series of zwitterionic brush polymers, poly(oxy(11-(3-sulfonylpropyltrimethylglycinyl)undecylesterthiomethyl)ethylene-co-oxy(n-dodecylthiomethyl)-ethylene)s (PECH-DMAPSm, where m is the mol% of DMAPS (sulfobetaine) end group) were synthesized. The polymers were found to form favorably into multi-bilayer structures, always providing hydrophilic, zwitterionic sulfobetaine end groups at the film surface. For the films, water sorption behavior and surface energy components were determined for the polymer films and the bacterial cells deposited on cellulose acetate membranes. The brush polymer films were found to suppress bacterial adherence significantly. An understanding of the suppression of bacterial adherence was attempted in terms of surface energies and thermodynamics. The results collectively indicate that the sulfobetaine-containing brush polymers are suitable for use in biomedical applications that require the reduced possibility of post-operative infection. |
| 저자 |
김미희, 김진철, 노예철, 정정운, 권원상, 안병철, 김경태, 고용기, 정성민, 권경호, 김영용, 이문호
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| 소속 |
포항공과대 |
| 키워드 |
Biocompatibility; Zwitterionic Brush polymer; Self-assembled structure
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| E-Mail |
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