| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells |
| 초록 |
Self-labeled magneto nanoprobes (SLMNs) were synthesized for one-step labeling of human mesenchymal stem cells (hMSCs) via non-invasive magnetic resonance (MR) image tracking. The surface of superparamagentic nanocrystals (SMNCs) were enveloped by tri-aminated polysorbate 80 (TP80) not only for enhancement of the affinity for hMSCs, but also to achieve increased colloidal stability in aqueous phase by the nanoemulsion method. The synthesized SLMNs exhibited excellent labeling efficiency of hMSCs and produced highly sensitive MR signals as well as safe cell cytotoxicity. |
| 저자 |
임은경, 양재문, 함승주, 허용민
|
| 소속 |
연세대 |
| 키워드 |
contrast agent; stem cell; labeling; tranfection agent; magentic nanocrystals
|
| E-Mail |
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