| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Preparation and characterization of UV-curable carrageenan derivatives to coat collagen sheet for BMP-2 releasing |
| 초록 | The Purpose of this study was photo-immobilization of BMP-2 using prepared azido-carrageenan derivative (Az-Carr) on collagen sheets and confirmed the effect of bone regeneration by release of the protein. Carrageenan as natural polymer had properties that it was biocompatible, low toxic, anti-viral activity and anti-coagulant for application to medical field. And, carrageenan was used in food and pharmaceutical applications for its gelling and thickening. Prepared Az-Carr identified by 1H-NMR and uv/vis spectrophotometer. Az-Carr was evaluated drug immobilization and releasing control with BSA protein using protein releasing test. To confirm enhanced bone regeneration, Ca2+, ALP assay and Alizarin Red S staining were performed. Acknowledgements This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and future Planning (No. NRF-2014R1A2A1A11052623) |
| 저자 | 한가득, 김은혜, 김재원, 노승현, 손태일 |
| 소속 | 중앙대 |
| 키워드 | BMP-2; Bone regeneration; Collagen sheet |
