초록 |
Designing, synthesizing and controlling plasmonic nanostructures such as Au and Ag nanoparticles with high precision and high yield are of paramount importance in optics, nanoscience, nanobiotechnology and materials science. It is particularly important and challenging to generate and control ~1-nm plasmonic gap or the shape and detailed structure of plasmonic nanoprobes for larger signal amplification and more quantitative signal output. Here, I will describe various functional molecule(e.g., DNA, protein, polymer, etc)-based synthetic strategies to build up new types of plasmonic nanoprobes with high structural controllability. The use of these plasmonic nanostructures including plasmonic nanogap structures and anisotropic nanostructures as excellent optical signal enhancement and biosensing platforms in detecting biomolecules sensitively, quantitatively and specifically will be mainly shown and discussed. |