| 초록 |
Stimuli-responsive block copolymers change their physical properties upon experiencing external stimuli such as temperature and pH. Block copolymers based on these polymers are gaining recent interest due to the promise in development of smart materials, drug delivery vehicles, and sensors. Stimuli-responsive polymers can be synthesized by adopting functional groups that exhibit selective binding with biologically important molecules such as sugars and nucleotides. Organoboronic acids have been studied as a monosaccharide receptors in an aqueous phase, which may find application in sensors and drug delivery systems for monosaccharide related human diseases such as diabetes. Our group focuses on the development of new organoboronic acid-containing polymers and block copolymers based on modified phenylboronic acids. Our goal is to synthesize boroxole-based block copolymers that switche their solubility in water in response to the presence of monosaccharides such as glucose. |
