| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, BEXCO(부산)) |
| 권호 |
14권 1호 |
| 발표분야 |
콜로이드계면화학 |
| 제목 |
Novel method for poly(amino acid) derivatives coatediron oxide nanoparticles using poly(succinimide) |
| 초록 |
Poly(amino acid)s would seem to have significant advantages over other polymers owing to their protein-like structure, water-solubility and absence of toxicity, antigenicity and immunogenicity. The biocompatible and water dispersible poly(amino acid) derivative was synthesized to act as the capping ligand of iron oxide nanoparticles. The hydrophilic poly(amino acid)s conjugated iron oxide nanoparticles form small spherical structure in aqueous solutions.The poly(amino acid)-coated nanoparticles showed no cytotoxicityand high T2 relaxivity coefficients. The poly(amino acid)-coatediron oxidenanoparticles demonstrate strong potential in bioapplications such as magnetic resonance imaging (MRI). |
| 저자 |
양희만, 박찬우, 조영민, 김종득
|
| 소속 |
KAIST |
| 키워드 |
iron oxide nanoparticles; MRI contrast agent; poly(amino acid); Poly(succinimide)
|
| E-Mail |
|
