| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 봄 (05/12 ~ 05/13, 전북대학교) |
| 권호 |
10권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Preparation and Drug Release Effect of Starch Grafted Acrylic Monomers Using γ-ray Irradiation |
| 초록 |
A bioadhesive material designed to perform as an oral drug-delivery system has to fulfill a series of requirements; in particular, the material must be nontoxic and nonirritant, and it must adhere to the mucosal surface. In this work, radiation-induced polymerization of acrylic monomers on the starch was performed at room temperature by exposing pregelatinized starches (2 wt% and 5 wt%) mixed with various amounts of acrylic monomer to a dose of 1.0 kGy/h. The gels so formed were cut into small pieces and dried in air. And then, the drug release behavior was investigated in various pH conditions. |
| 저자 |
임윤묵, 정찬희, 전준표, 김윤혜, 최재학, 강필현, 노영창
|
| 소속 |
한국원자력(연) |
| 키워드 |
γ-ray radiation graft; starch; biocompatibility; drug delivery system
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| E-Mail |
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