| 학회 |
한국재료학회 |
| 학술대회 |
2014년 가을 (11/27 ~ 11/28, 대전컨벤션센터) |
| 권호 |
20권 2호 |
| 발표분야 |
D. 바이오 재료(Biomaterials) |
| 제목 |
Synthesis and Characterization of Amphiphilic Chitosan Modified Particles for Tissue Engineering |
| 초록 |
Amphiphilic chitosan was developed by conjugating octyl groups as hydrophobic moieties and phenyl propionic acid as hydrophilic groups onto the amino groups at chitosan’s C-2 position. A certain amount of –NH2 was retained in the structure of the chitosan derivative through protection by phthalic anhydride. The chemical structures and degree of N- and O- substitution of the chitosan derivatives were characterized by FTIR and elemental analysis. In vitro studies demonstrated good biocompatibility and surface properties tuned for cell. The amphiphilic property for convenient self-assembly and the preserved –NH2 groups make the resultant chitosan soluble in water and potentially applicable in preparing stable chitosan particles, a demanding cell and drug-carrier in medical and pharmaceutical sciences. |
| 저자 |
Celine Abueva1, Young-Ki Min2, Byong-Taek Lee3
|
| 소속 |
1Department of Regenerative Medicine, 2College of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
Tissue engineering; Chitosan; Amphiphile
|
| E-Mail |
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