| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터) |
| 권호 |
14권 2호 |
| 발표분야 |
Bio-active, functional macromolecules and nanomaterials |
| 제목 |
Tumor-Targetable Hyaluronic Acid Nanoparticles for Drug Delivery and Biomedical Imaging |
| 초록 |
Polymeric Nanoparticles have been developed as the carrier of anti-cancer drugs and/or imaging agents for effective therapy and diagnosis of cancer. However, the tumor targeting efficienty of the nanoparticles are still one of the important issues. In this study, we prepared hyaluronic acid(HA)-based nanoparticles for tumor targeting. The detailed biodistribution of the nanoparticles in the tumor-bearing mice was investigated using the optical imaing techniuqe. In addition, in vivo therapeutic effect of drug-loaded nanoparticles on the tumor was evaluated.Overall it was evident that HA nanoparticles are promissing carrier for delivery of anti-cancer drugs as well as imaging agents. |
| 저자 |
박재형 |
| 소속 |
경희대 |
| 키워드 |
Tumor targeting; drug delivery; molecular imaging
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| E-Mail |
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