학회 |
한국고분자학회 |
학술대회 |
2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터) |
권호 |
42권 1호 |
발표분야 |
의료용 고분자 부문위원회 I |
제목 |
Chondrocyte Study in Cartilage Cells Using Gellan-gum/Chondroitin sulfate Hybrid Scaffolds |
초록 |
The chondroitin sulfate (CS) has been found to induce slow but sustained relief with respect to the clinical symptoms of osteoarthritis (OA), and these effects persist for long periods after treatment. In fact, chondroitin sulfate has been proven to be a structurally improved arthritis drug that can relieve, delay or stabilize joint inflammation in many animal experiments and clinical trials, thus providing symptom relief in long-term. In this study, we investigated the effect of gellan gum scaffolds containing chondroitin for treating osteoarthritis in vitro. The chondroitin content in the scaffolds was chosen as 10, 20 and 30%. The scaffolds characterizations were performed by SEM and FTIR. The cell adhesion and proliferation rate were confirmed by MTT assay and gene expression by RT-PCR. |
저자 |
국연지, 최일남, 김창현, 백종선, 전하얀, 송정은, 강길선
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소속 |
전북대 |
키워드 |
: Chondroitin Sulfate; Gellan Gum; Hydrogel Scaffold
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E-Mail |
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