| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 봄 (04/12 ~ 04/13, 제주 ICC) |
| 권호 |
32권 1호 |
| 발표분야 |
나노바이오기술용 고분자(의료용 고분자 부문위원회) |
| 제목 |
Cell adhesion and protein adsorption onto PEO or PEO-sulfonate grafted surface |
| 초록 |
The biocompatibilty of materials is decided by the surface properties including hydrophobicity/hydrophilicity. Hydrophilic surfaces or PEO-grafted surfaces are known to suppress protein or cell adhesion. In this study, PEO or PEO-sulfonate was grafted onto polymers by UV irradiation utilizing photoactive azide end group. The surfaces photo-grafted by PEO or PEO-sulfonate were characterized by the dynamic contact angle measurement and ESCA analysis. The cell adhesion study was conducted on the modified surfaces to investigate the effect of PEO or PEO-sulfonate groups grafted. The modified surfaces exhibited the increased hydrophilicy and decreased cell adhesion. The protein adsorption was also studied by the QCM-D (quartz crystal microbalance with dissipation monitoring) method. |
| 저자 |
김연주, 김미혜, 정효숙, 태기융, 김영하
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| 소속 |
광주과학기술원 |
| 키워드 |
biocompatibilty; PEO-sulfonate; cell adhesion; protein adsorption
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| E-Mail |
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