초록 |
Generally, riboflavin phosphate (RFP) is used as a photo-initiator with UV irradiation to generate free radicals, and they are utilized to form crosslinks. Here, we improved the mechanical properties of skin tissues using RFP-mediated free radical reactions with blue light instead of UV, which has been known as a negative effect on the skin. After the RFP treatment to the skin tissues, blue light was irradiated. Mechanical properties of resultant skin tissues were measured using UTM, and the skin degradation rate was assessed. The biocompatibility of the free radical reaction by RFP was evaluated by cell proliferation. |