| 초록 |
Alginate-chitosan Janus particles were prepared in order to develop a biocompatible embolization material having unique assembly structures. Sodium alginate, an anionic polysaccharide, can form a polyelectrolyte complex with chitosan, a cationic polysaccharide. One side of a polypropylene-mesh filled with sodium alginate solution was placed in chitosan solution, followed by gelation. This system was characterized by Electron microscopy, Differential scanning calorimetry, Fourier transform infrared spectroscopy and Scanning electron microscopic studies. Proper wetting characteristics of mesh surface and premade particle surface were critical in developing Janus structures. Due to the ionic interactions between alginate and chitosan, the interface between the two compartments of Janus structures did not suffer from interfacial failure problems. To add tracking functionality to the particles, gold and superparamagnetic nanoparticles were loaded before gelation. |
