| 학회 | 한국공업화학회 |
| 학술대회 | 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 | 21권 1호 |
| 발표분야 | (콜로이드계면화학)첨단 소재 및 바이오 기술 분야의 표면화학 연구동향 |
| 제목 | Direct measurements of interaction forces between lipid bilayers using Surface Forces Apparatus (SFA) |
| 초록 | Interaction forces between lipid membranes (bilayers) were directly measured using a Surface Forces Apparatus (SFA). This talk contains two different but closely related works. In the first part of this talk, the effects of Myelin Basic Protein (MBP, an inter-membrane protein) concentrations and lipid compositions on the inter-membrane adhesion forces will be discussed. As model lipid membranes, two different compositions of lipid mixtures are used: (i) the composition of a healthy myelin, and (ii) the composition of a diseased myelin. In the second part of the talk, a pressure induced hemifusion event of two supported model lipid bilayers have been imaged using a Fluorescence-SFA. Using this technique, evolution of the membrane thickness and the rearrangement of lipid domains are monitored simultaneously. Also, the effects of applied pressure on the rate of bilayer hemifusion is investigated. |
| 저자 | 이동욱 |
| 소속 | 울산과학기술원 (UNIST) |
| 키워드 | Lipid bilayer; Lipid domain; Interaction force; membrane hemifusion |
