화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 봄 (05/13 ~ 05/14, BEXCO(부산))
권호 14권 1호
발표분야 정밀화학 기술의 응용
제목 Application of Superparamagnetic Iron Oxide Nanoparticles for Tissue-specific Imaging and Therapy
초록 Mannan-coated superparamagnetic iron oxide nanoparticles (Mannan-SPION) were developed to be specifically delivered to macrophages in lymph node by receptor-mediated endocytosis. In another application, positively charged SPION-loaded polymersome tethering PEG as a hydrophilic corona layer was prepared to deliver therapeutic genes to target sites, which was monitored by MRI concomitantly. Furthermore, Labeling with iron oxide particles has been used to track mesenchymal stem cells via magnetic resonance imaging (MRI) to monitor the progress of the stem cells in scarred heart.
저자 박인규
소속 전남의대 의생명과학과 / 전남대병원 심장질환 치료기술개발 특성화센터
키워드 Superparamagnetic iron oxide nanoparticles; polyethylenimine; magnetic resonance imaging; transfection
E-Mail