초록 |
Hybrid nanoparticles based on a conjugated polymer and iron oxide nanocrystals were prepared as a multi-functional nanomaterials applicable to simultaneous magnetic resonance imaging(MRI), photoacoustic imaging and photothermal therapy by absorbing near infrared light. These nanoparticles were assembled by forming a phase-separated thin film of the conjugated polymer, iron oxide nanocrystals and a phospholipid, followed by shattering the film via water penetration through polar regions of the film upon ultrasonication. As a result, water-dispersed hybrids of magnetic and conjugated polymer nanoparticles were successfully fabricated and simultaneously presented MRI, pho-toacoustic and photothermal features that were most remarkable at a mixing ratio with the most well organized ordering in molecular assembly structures. |