| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Thermally Responsive Polymeric Hydrogels for Fluorescent Color Switching by FRET Distance Modulation |
| 초록 |
In this study, we developed a hydrogel-based fluorescent thermometer using organic dyes labeled temperature-responsive copolymer system. Poly(N-isopropylacrylamide) (PNIPAM) was chosen as a thermally-responsive spacer between blue and green emitting dyes in order to make conformational change by temperature, while randomly polymerized acrylates were used to regulate water swelling ratio of the hydrogel. The spatial proximity between Förster resonance energy transfer (FRET) donors and acceptors incorporated in the hydrogel can be tuned via thermo-induced collapsing and swelling of the platform at the lower critical solution temperature of PNIPAM, leading to the facile modulation of FRET efficiencies. In addition, our hydrogel system showed excellent reversibility, indicating an ideal platform for biological and environmental applications. |
| 저자 |
박찬호1, 배진우1, 이준혁1, Kin Liao2, 김범준1
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| 소속 |
1한국과학기술원, 2Khalifa Univ. |
| 키워드 |
Poly(N-isopropylacrylamide); Förster resonance energy transfer; Stimuli-responsive hydrogels
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| E-Mail |
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