| 초록 |
Electrpspun fibers have been used as promising artificial vascular scaffolds in the field of tissue engineering. In this study, biodegradable poly(L-lactide-co-caprolactone) (PLCL) and marine collagen (MC) were used to prepare the electrospun nanofibers for elastic and soft tissue scaffolds. The PLCL copolymer blended with MC was electrospun into nanofibers from a 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) solution with MC content, a tip-target distance (TTD), voltage, a nozzle size and the electrospinning flow rate. The electrospun PLCL/MC nanofibers were charaterized by using a scanning electron microscopy (SEM). As the MC content, TTD, voltage, nozzle size, and flow rate increased, the diameter of the nanofibers decreased. Neat PLCL exhibited the highest average diameter. Thus, PLCL/MC (70/30) blends may have the potential for tissue scaffold engineering |
